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Charity Christmas Concert

A Christmas Celebration with the Holst Singers

We are pleased to announce arrangements for our 2018 Christmas Concert with the Holst Singers in aid of bronchiectasis and lung infection research. The concert will be taking place at a NEW VENUE this year, ST PANCRAS CHURCH, Euston Road, NW1 2BA on Friday, 7th December at 7.30pm.

St Pancras Church is a beautiful historic building which is 200 years old and has a Grade I listing from English Heritage, as an important early example of the Greek Revival architecture.  It is located opposite Euston Station and is a short skip and a hop from UCL and UCLH, and we are really excited to secure this new venue.

The concert will feature well-known traditional carols as well as more contemporary Christmas music. The Holst Singers are one of Britain’s foremost choirs.  Our guest readers this year are well-known former BBC Radio 4 presenters, Charlotte Green and Brian Perkins.

The evening will comprise of a mixture of Christmas music performed by the choir, audience carols and seasonal readings.  There will be wine and mince pies available before and after the concert and during the interval.

For tickets (£25) and further information, please contact Jane Walker tel: 01732 366346 or email missjanewalker@hotmail.com

Tickets are also available online from: https://bmholstsingersconcert.bpt.me

We hope you are able to join us for a feast of seasonal music and a most wonderful start to the festive season!

Donation received from Profile Pharma, towards the costs of staging this concert

 

 

Summer Newsletter 2018 – Answers to Youngest Ever Football Quiz

At the age of 17, who became the youngest footballer to play at a World Cup?

  • Pele

Who is England’s youngest ever goalkeeper?

  • Jack Butland: Butland made his debut in 2012, breaking a record that had stood since Billy Moon first played for England in 1888.

Whose goal against Macedonia made him the youngest player to score for England?

  • Wayne Rooney: Rooney, who was still playing for Everton, was 17 years old at the time. Two months later, in April 2003, he became the youngest player to start a match for England.

Who holds the record for being the youngest manager to win a major European trophy?

  • André Villas-Boas: Villas-Boas was only 33 when he won the Europa League with Porto

Get out of Breath for #Breathtember

September is #Breathtember – Global Pulmonary Fibrosis Awareness Month

 Get out of Breath for #Breathtember

Tweet Tweet!

https://www.breathingmatters.co.uk/wp-content/uploads/2013/06/twitter.png

To help raise awareness, we would ask that supporters tweet different challenges each day in September including the term ‘#Breathtember and to ask their followers to retweet and share this information as widely as possible.

Think outside the box for your challenges – getting out of breath for you could mean:

  • Cycling around your local park
  • Doing a colourful or musical 5K/10K run or walk
  • Singing until you are out of breath
  • Walking over the wonderous London bridges
  • Blow bubbles!
  • Skydiving
  • Or just simply walking up the stairs!

The important thing is that you tweet your challenge every day including the term ‘#Breathtember’ to raise awareness of pulmonary fibrosis.  Add a photo if you like.  This September, we want as many people as possible to see the term ‘#Breathtember’.  To make the biggest impact, the aim is to get the term ‘#Breathtember’ to trend.

Follow us on Twitter for further details: @Breathingmatter 

twitter

 

 

Inspiring Students to become Scientists of the Future

The William Perkin story started with a child being fascinated by science – and setting out to ask ‘Why?’ and ‘What for?’  What a perfect school for a visit to inspire students to go into research.

Breathing Matters and Dr Pascal Durrenberger, a STEM ambassador and UCL Respiratory scientist, took part in the William Perkins CofE High School Founders’ Day celebrations on Friday 11th May 2018 as part of the Big Bang London Programme @ Schools Events.  The Big Bang programme actively helps promote STEM subjects throughout the UK (Science, Technology, Engineering, Maths).

Our workshop was called “The Lung Project”. Dr Durrenberger gave an inspirational talk to the students explaining how and why he got into science research.

We then had three main activities for the children:

  1. X-man Pneumatico (a ping-pong breathing game)
  2. Play Histologist (identifying lung diseases on microscope slides)
  3. Help the Lung Scientist (medical quiz).

There were points to win on all sessions and we gave out prizes to the students with the most points.

The Founders Day included many eminent scientists, including Lord Professor Robert Winston (of a ‘Child of our Time’ fame) and Professor Sara Rankin from Imperial College.

Feedback from the day was very positive with numerous students specifically mentioning our workshop: ‘The best thing I did today was… “Breathing session”. “Lung Workshop”.

A special thank you goes to Michelle Drew from Waterstones Piccadilly for donating books as prizes. Funding was also provided by Breathing Matters.

Cycling Matters at Cyclotopia

The sun shone over the Velodrome as over 100 riders enjoyed the bikefest of activities which can only mean one thing – Cyclotopia was back again!

Cyclists of all ages and abilities pedalled over the smooth traffic-free road circuit, challenged themselves on the bumpy mountain trail and sped around the Olympic Velodrome track, the fastest in the world.

The event brought in almost £6000 for Breathing Matters and Haematology Cancer Care, both UCLH Charities.

Thank you to our amazing volunteers, without whose help this event could not have taken place.  We are indebted to you all.

Thank you also to Jules Mountain who donated his book as prizes to our fastest cyclists, and to the amazingly professional staff at the Lee Valley VeloPark.

Finally, we thank our photographers Mark Mbm and Gerwyn Jones for the lovely photos:

 

Spring 2018 Newsletter – Answers to the 2017 UK Firsts Quiz

 

Q: Who was announced as the 13th Doctor Who?

A: Jodie Whittaker

 

Q: What is the biggest selling single of 2017?

A: ‘Shape of You’, By Ed Sheeran

 

Q: Who won the BAFTA for Best Film in 2017?

A: La La Land

 

Q: What was the best selling book of 2017? [Data from the Guardian]

A: Non-fiction = ‘5 Ingredients, Quick and Easy Food’, by Jamie Oliver ‘- sold 716K

A: Fiction = ‘Bad Dad’, by David Walliams – sold 568K

 

Q: Who won Strictly Come Dancing?

A: Joe McFadden

 

Q: What were the top 3 boys and girls names of 2017? [Data from the Office of National Statistics]

Boys                            Girls

Noah                           Olivia

Harry                          Amelia

Oliver                          Emily

Spring 2018 Newsletter is Here

For the Spring 2018 Newsletter, please click here

Ride London 100 Places Now Available

Are you a keen cyclist and want a serious challenge?  How about doing the Prudential Ride London 100 on Sunday, 29th July 2018.

Ride London really is a true gem of an event starting at the iconic Olympic VeloPark in Lee Valley, cycling 100 miles of closed roads past London landmarks and through the stunning Surrey countryside (and hills!) and finishing in champion-style at the Mall outside Buckingham Palace!  It’s the UK’s largest world-class festival of cycling.

You don’t have to be an elite cyclist, however, and can choose a start time based at your level – you just need to be able to finish the course in under 9 hours and be over 18.  More info for riders can be found here.

Breathing Matters has a limited number of guaranteed places for this year’s event.  Registration is £50 and we ask that you raise £450 for Breathing Matters.  To sign up, email us at breathingmatters@ucl.ac.uk

The deadline for sign ups is Tuesday, 22nd May 2018, so don’t delay.

 

 

 

 

 

 

Bronchiectasis Newsround

 

Upcoming  News:

In April, a new research registrar, Dr Jocelyn Hall, will join the lung infection group for at least one year. She will be dividing her time between working with patients in the bronchiectasis clinic and on the ward, and starting some new research projects into bronchiectasis. In particular, she will be investigating how bronchiectasis affects the immune response to important causes of lung infection such as Streptococcus pneumoniae.  The Brown group has new methods of looking at how someone’s immune system recognises the bacteria and these will be used in patients with bronchiectasis to see whether there are any weaknesses in their ability to fight off lung bacteria that might mean they are more likely to get infections.

 

Research Paper:

In November, new UCL research into bronchiectasis findings were published in the European Respiratory Journal.  In this study by one of our previous research registrars Dr Arash Saleh and led by Dr John Hurst, we looked into risk factors for cardiovascular disease (heart attacks, angina and strokes) in patients with bronchiectasis. We previously published a paper using data from GP patient databases to show that people with bronchiectasis have roughly double the chance of having cardiovascular disease that would be expected. In the new paper, we have looked more closely at 101 people with bronchiectasis using a special ultrasound machine to measure the stiffness of the blood vessels in their arm.  What we found was that the arteries were stiffer than expected, especially in patients with reduced breathing capacity or frequent infective exacerbations. This is important as stiffer arteries are more likely to cause cardiovascular disease. Hence these results back up the previous epidemiology paper and further demonstrate that, as well as looking after the lungs, we need to think about reducing cardiovascular risk in patients with bronchiectasis.

 

 

Our Most Important Lung Fibrosis Paper to Date

We are delighted to announce the publication of our collaboration with the Insititute of Nuclear Medicine and our most important lung fibrosis paper to date. This work investigates the use of molecular imaging to more accurately determine disease severity in patients with pulmonary fibrosis.

Win T, Screaton NJ, Porter JC, Ganeshan B, Maher TM, Fraioli F, Endozo R, Shortman RI, Hurrell L, Holman BF, Thielemans K, Rashidnasab A, Hutton BF, Lukey PT, Flynn A, Ell PJ, Groves AM. Pulmonary 18F-FDG uptake helps refine current risk stratification in idiopathic pulmonary fibrosis (IPF). Eur J Nucl Med Mol Imaging. 2018 Jan 16. [Epub ahead of print].

For the last 5 years, Breathing Matters has collaborated on a programme investigating the ability of PET scanning to more accurately predict prognosis in individual patients with IPF and other forms of lung fibrosis.

[Combined high resolution CT image (Left) and PET image (Right) in a patient with IPF. The CT images (A) show honey comb lung (arrow) and PET images show high signal in the honey comb area (black, at site of broken arrow). Groves et al J. Nucl Med. 2009;50:538-45.]

The newly published paper in the European Journal of Nuclear Medicine, consisted of a unique 10-year prospective study of 113 IPF patients (the largest PET study in IPF) and the first of its kind to evaluate the use of FDG (glucose metabolism) PET scanning to predict prognosis and disease progression against the current standard, Gender Age Physiology (GAP) scoring system.

The findings demonstrate that FDG (glucose metabolism) PET scanning can help identify patients with IPF who are at increased risk of death and might therefore benefit from early treatment.

The figure below shows, for the first time,  that patients with IPF who have a higher lung glucose metabolism are significantly ( p<0.003) more likely to deteriorate rapidly, despite having features that would conventionally place them in a good prognostic group. This data suggests that current treatment guidelines may need to be reviewed, as currently patients placed in a conventionally favourable group are not recommended for treatment.  This novel imaging biomarker may allow us to evaluate new treatments more quickly by looking for changes in PET signal in individual patients.  This will mean that smaller cohorts of patients will be needed for clinical efficacy trials, with a reduction in time to bring new medicines to patients.

Dr Porter reports, “This is a potential game changer in the stratification  of patients with pulmonary fibrosis, giving additional information that complements the current GAP score and allows us to more accurately predict outcomes for individual patients.  This means that we can reassure patients with a low glucose uptake on the scan; but intensify follow-up, treatment and early transplant referral in those patients with high glucose uptake. This is better for patients and allows us to provide a more effective and efficient ILD service”.